The unmet need in the ROS1-positive lung cancer patient population is significant. Prior to Epitomics, Dr. Li was Vice President at Kenson Ventures, LLC, where he served on Board of Directors and observers to the Board for biotech companies. I look forward to working with the team and applying our collective expertise to advance and eventually deliver transformative medicines to cancer patients, said Dr. Li. About CBC GroupCBC Group, formerly known as C-Bridge Capital, is a healthcare dedicated private equity firm, focused on growth and late stage, early stage and incubation opportunities across the healthcare industry. Dr. Li served as Chairman and CEO of TP from 2013 to 2018 and continued.
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"We are excited to announce our first in-license as a company and strategically expand our clinical stage portfolio, specifically within GI tumors. Turning Point went public on NASDAQ in April 2019 (Ticker: TPTX). LaNova Medicines announced that it has entered into an exclusive license agreement with Turning Point Therapeutics (NASDAQ: TPTX) to develop and commercialize LM-302, a novel antibody drug conjugate (ADC) targeting Claudin18.2, in the U.S. and rest of the world, excluding Greater China and South Korea. Turning Point Therapeutics, Inc. announced that TPX-0022, the company's inhibitor of MET and the associated cancer signaling pathways of SRC and CSF1R, has been granted orphan drug designation by the Food and Drug Administration (FDA) for the treatment of patients with gastric cancer, including gastroesophageal junction adenocarcinoma. Turning Point USA ( TPUSA ), or Turning Point, is an American conservative nonprofit organization that advocates to identify, educate, train, and organize students to "promote the principles of freedom, free markets, and limited government." [3] [4] [5] [6] [7] The organization was founded in 2012 by Charlie Kirk and Bill Montgomery. Al hacer clic en Aceptar todo, aceptas que Yahoo y nuestros socios procesarn tu informacin personal y utilizarn tecnologas como cookies para presentarte anuncios y contenido personalizados, evaluar anuncios y contenido, obtener datos clave sobre la audiencia y desarrollar productos. The ongoing study is currently active in 11 countries globally and enrolling patients with ROS1-positive advanced non-small cell lung cancer (NSCLC) and NTRK-positive solid tumors. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including but not limited to (1) Zai Labs ability to obtain additional future funding, (2) Zai Labs results of clinical and pre-clinical development of its drug candidates, (3) the content and timing of decisions made by the relevant regulatory authorities regarding regulatory approvals of Zai Labs drug candidates, (4) Zai Labs ability to generate revenue from its drug candidates, (5) the effects of the novel coronavirus (COVID-19) pandemic on general economic, regulatory and political conditions and (6) other factors discussed in Zai Lab's Annual Report on Form 20-F for the fiscal year ended December 31, 2019, filed on April 29, 2020, and its other filings with the Securities and Exchange Commission.
More information about the ongoing TRIDENT-1 study of repotrectinib may be found by searching clinical trial identifier NCT03093116 athttps://clinicaltrials.gov. Turning Point Therapeutics is registered under the ticker NASDAQ:TPTX . The Investor Relations website contains information about Turning Point Therapeutics, Inc.'s business for stockholders, potential investors, and financial analysts. . Our collaboration with Zai Lab is a strategic step to potentially accelerate the development of repotrectinib in Greater China.. SAN DIEGO, May 17, 2021 (GLOBE NEWSWIRE) -- Turning Point Therapeutics, Inc. (NASDAQ: TPTX), a precision oncology company developing next-generation therapies that target genetic drivers of cancer . Contacts: Media in US and Europe: Mark Corbae Senior Vice President Westwicke PR +1 (203) 682-8288 mark.corbae@icrinc.com Media in China: Edmond Lococo Senior Vice President ICR Asia +86 (10) 6583-7510 edmond.lococo@icrinc.com, A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/c61d9da7-7d34-4638-9646-4fe93ec9ae97, https://www.globenewswire.com/NewsRoom/AttachmentNg/c61d9da7-7d34-4638-9646-4fe93ec9ae97.
NEW YORK & SAN DIEGO--(BUSINESS WIRE)-- Bristol Myers Squibb (NYSE:BMY) and Turning Point Therapeutics, Inc. (NASDAQ:TPTX) today announced a definitive merger agreement under which Bristol Myers Squibb will acquire Turning Point Therapeutics for $76.00 per share. The successful implementation of our strategy enables us to rapidly and efficiently discover and advance proprietary drug candidates with the most desirable pharmacological features into clinical studies. "LaNova Medicines is focused on discovery and development of innovative medicines in oncology. Under the terms of the licensing agreement, LaNova will receive an upfront payment of $25 million and will be eligible to receive up to an additional $195 million in development and regulatory milestone payments; in addition, LaNova is eligible to receive commercial sales milestones, and tiered royalties ranging from mid-single digit to mid-teens percentages on net sales (subject to customary deductions). Our discovery approach is informed by target structure biology and capitalizes on structure-based drug design. Zai Lab anticipates that subsequent events and developments will cause Zai Labs expectations and assumptions to change and undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law. In China, there is only one approved targeted therapy for patients with advanced ROS1-positive lung cancer and despite its efficacy, most patients eventually acquire resistance, said Dr. Lu Shun, Director of Chinese Lung Cancer Association. If approved, repotrectinib has the potential to be the standard of care for ROS1-positive patients with advanced non-small cell lung cancer in China..
The transaction was unanimously approved by both the Bristol Myers Squibb and Turning Point Therapeutics Boards of Directors and is . Such statements constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. It also has demonstrated efficacy in gastric and pancreatic cancer xenograft models.
Their latest funding was raised on Oct 26, 2020 from a Post-IPO Equity round. For additional information about the company, please visitwww.zailaboratory.comor follow us atwww.twitter.com/ZaiLab_Global. Turning Point will also be eligible to receive mid-to-high teen royalties based on annual net sales of repotrectinib in Greater China. Haz clic en Gestionar ajustes para obtener ms informacin y gestionar tus opciones. Zai Lab Forward Looking StatementsThis press release contains statements about future expectations, plans and prospects for Zai Lab, including, without limitation, statements regarding the prospects of and plans for commercializing repotrectinib in mainland China, Hong Kong, Macau and Taiwan. The company is driven to develop therapies that mark a turning point for patients in their cancer treatment. Nosotros, Yahoo, somos parte de la familia de marcas de Yahoo. SAN DIEGO, March 01, 2021 (GLOBE NEWSWIRE) -- Turning Point Therapeutics, Inc. (NASDAQ: TPTX), a precision oncology company developing next-generation therapies that target genetic drivers of. Zai Labs vision is to become a fully integrated biopharmaceutical company, discovering, developing, manufacturing and commercializing its portfolio in order to impact human health worldwide. As Chairman and CEO, Dr. Li led TP for 5 years and successfully raised 4 rounds of venture financing for $147 million in total from leading biotech investors. VP, Cancer Biology & Translational Research at Turning Point Therapeutics o Created & led productive in vitro & in vivo pharmacology teams: TPX-0046 . He earned his M.B.A. from Haas School of Business, University of California, Berkeley. The company's lead drug candidate, repotrectinib, is a next-generation kinase inhibitor targeting the ROS1 and TRK oncogenic drivers of non . The preliminary clinical activity and safety data generated to date for repotrectinib represent a promising clinical profile. Dr. Li served as Chairman and CEO of TP from 2013 to 2018 and continued to serve as a Director until TP completed a successful $191 million IPO on Nasdaq in April 2019. He received his Ph.D. in biochemistry from Ohio State University, where he was a University Presidential Fellow, and his B.S. Zai Lab Billy Cho, CFO +86 137 6151 2501 billy.cho@zailaboratory.com: Turning Point Therapeutics Jim Mazzola jim.mazzola@tptherapeutics.com 858-342-8272 Media: Ryo Imai / Robert Flamm, Ph.D. Which funding types raised the most money? Our target selection is driven by deep insights into disease biology and molecular pathways. WILMINGTON, Del., Nov. 04, 2019 (GLOBE NEWSWIRE) -- NiKang Therapeutics, an early stage biotech company focused on discovering and developing innovative small molecule oncology medicines to help patients with unmet medical needs, today announced the appointment of Y. Peter Li, Ph.D., MBA, as Chief Executive Officer and Board Director. Informacin sobre tu dispositivo y conexin a Internet, como tu direccin IP, Actividad de navegacin y bsqueda al utilizar sitios web y aplicaciones de Yahoo. Turning Point Therapeutics is a clinical-stage precision oncology company with a pipeline of internally discovered investigational drugs designed to address key limitations of existing cancer therapies. About Zai Lab Zai Lab(NASDAQ:ZLAB) is an innovative commercial stage biopharmaceutical company focused on bringing transformative medicines for cancer, infectious and autoimmune diseases to patients inChinaand around the world. Zai Lab anticipates opening additional sites for the TRIDENT-1 Phase 2 registrational clinical study of repotrectinib. Crystal Qin, Founder, Chairman and CEO of LaNova Medicines. 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